For vaccination of healthy dogs 6 weeks of age or older as an aid in preventing canine distemper caused by canine distemper (CD) virus, infectious canine hepatitis (ICH) caused by canine adenovirus type 1 (CAV-1), respiratory disease caused by canine adenovirus type 2 (CAV-2), canine parainfluenza caused by canine parainfluenza (CPI) virus, enteritis caused by canine coronavirus (CCV) and canine parvovirus (CPV), and leptospirosis caused by Leptospira canicola, L. grippotyphosa, L. icterohaemorrhagiae, and L. pomona.
This product is available as a special order only. Please allow 5-7 additional days for processing.
UPCO ships cold items as soon as possible, but ONLY ships temperature sensitive items Monday-Thursday when delivery dates for your selected location fall during the same week it is shipped even if expedited service is selected. EX: If you choose overnight delivery for an order placed on Friday, it will ship on Monday for Tuesday delivery. This avoids weekend transit where items will sit in unknown temperature conditions until the following week. If you need a cooler item expedited and delivered by a specific date, please contact our customer service department at 816-233-8800 for further assistance.
Expedited Shipping Required
(May – September)
Due to rising temperatures during the warmer months of the year, expedited shipping will be required for all perishable products purchased and shipped from UPCO. Requiring air shipping service helps ensure product stability upon receipt and minimizes duration of heat exposure.
VANGUARD Plus 5 L4 CV is a freeze-dried preparation of attenuated strains of CDV, CAV-2, CPiV, CPV, CCV and inactivated whole cell cultures of L. canicola, L. grippotyphosa, L. icterohaemorrhagiae, and L. pomona.
Leptospira cells are extensively rinsed via a proprietary diafiltration process which helps to reduce extraneous material in the vaccine.
Safety documented in a large-scale, multicenter study.
Efficacy confirmed against the common canine Leptospira serovars.
Covered by the Companion Animal Immunization Support Guarantee.
We cannot ship vaccines outside of the US.
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How to Use
Directions: Aseptically rehydrate the freeze-dried vaccine (Vanguard Plus 5 L4) with the accompanying vial of adjuvanted liquid vaccine (Vanguard CV), shake well, and administer 1 mL subcutaneously or intramuscularly. Healthy dogs should receive 2 doses administered 3 weeks apart, followed by a single dose of Vanguard CV 3 weeks later. To avoid the potential for maternal antibody interference, dogs vaccinated at less than 9 weeks of age should receive 3 doses of the combination vaccine, each administered 3 weeks apart. Annual revaccination with a single dose is recommended.
Duration of immunity has not been established.
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